Principal Statistical Programmer

Job Description

• This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Principal Statistical Programmer in the United States. This senior-level role sits at the core of clinical and pharmaceutical research, leading statistical programming efforts that directly support clinical trials, regulatory submissions, and real-world evidence generation. You will oversee complex programming projects, ensuring high-quality statistical outputs that inform critical drug development decisions. Acting as both a technical leader and project lead, you will coordinate cross-functional teams, manage timelines and deliverables, and ensure compliance with industry standards. The role combines deep SAS expertise with leadership responsibilities, including mentoring junior programmers and guiding methodological best practices. You will collaborate closely with statisticians, clients, and internal stakeholders to translate analysis plans into robust datasets, tables, and figures. This is a highly impactful position in a remote, collaborative environment where precision, scientific rigor, and operational excellence are essential.
• Accountabilities You will lead statistical programming projects end-to-end, ensuring accurate, timely, and compliant delivery of clinical analysis outputs while guiding teams and improving programming standards across studies. Lead one or more statistical programming project teams to deliver analysis datasets, tables, figures, and listings on time and within quality standards Manage project resources, timelines, budgets, and study-level metrics across multiple concurrent initiatives Collaborate with statisticians and clients to review analysis plans and implement study-specific requirements Develop, review, and maintain analysis dataset specifications and complex SAS programs Produce and validate statistical outputs, including SDTM/ADaM datasets, summaries, and regulatory documentation Prepare and package final deliverables, including DEFINE.xml, Reviewer’s Guides, and submission-ready documentation Serve as a technical consultant and represent statistical programming in cross-functional and client meetings Mentor junior programmers and contribute to training, process improvement, and macro library development Requirements You bring deep expertise in SAS programming and clinical research environments, combined with strong leadership capabilities and a solid understanding of pharmaceutical data standards and statistical methodologies. Bachelor’s degree or equivalent in a relevant field 10+ years of SAS programming experience, including at least 7 years in the pharmaceutical or clinical research industry Strong expertise in SAS/Base, SAS Macro programming, and ODS outputs (Word, Excel, XML) Extensive experience with CDISC standards (SDTM, ADaM) and clinical data structures Proven ability to develop complex SAS macros and optimize programming workflows Solid understanding of statistical concepts and clinical analysis methodologies Experience leading programming teams and managing multiple concurrent projects Strong skills in technical documentation, analysis specifications, and regulatory deliverables Excellent communication, organization, and stakeholder management abilities Proficiency in Microsoft Word and Excel for technical and reporting purposes Benefits Fully remote work opportunity across the United States Competitive salary package 401(k) with company match Comprehensive medical, dental, and vision insurance Health Savings Account (HSA) and Flexible Spending Account (FSA) options Paid time off (including discretionary PTO) and paid holidays Tuition reimbursement and career development opportunities Employee assistance and wellness programs Short-term and long-term disability coverage Life insurance coverage Telemedicine and virtual healthcare access Adoption assistance programs Employee discount programs Flexible and supportive work environment focused on growth and well-being
• How Jobgether works: We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team. We appreciate your interest and wish you the best! Why Apply Through Jobgether? Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time. #LI-CL1
• We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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