Vice President of Engineering, UX/Commercial Applications
natera • US Remote
Posted: March 2, 2026
Job Description
Vice President of Engineering, UX/Commercial Applications
Reports to: SVP, UX Products & Engineering
Organization Size: 100+ Engineers
Position Summary: Natera is seeking a Vice President of Engineering, UX/Commercial Applications to lead a 100+ person engineering organization responsible for our commercial software platforms. This leader will focus on strengthening execution, raising engineering standards, and advancing AI-enabled product and development capabilities.
Scope includes:
-
Patient and Provider Portals
-
EMR integrations & interoperability
-
Internal service and operational systems
-
Omni-channel communications
-
Billing and revenue platforms
-
AI-powered chat and voice automation
Key Responsibilities
Engineering Leadership & Execution
-
Lead and scale a 100+ engineer organization through Directors and Sr. Directors
-
Improve delivery predictability, engineering velocity, and production quality
-
Strengthen planning, estimation, and development processes
-
Raise the bar on accountability and ownership
-
Develop strong engineering leaders and succession depth
Technical Depth & Architectural Rigor
-
Strong background in distributed systems and cloud-native architectures (AWS preferred)
-
Experience building scalable, highly available platforms
-
Deep understanding of modern web stacks (APIs, React, TypeScript, services)
-
Experience leading platform modernization and reliability improvements
-
Comfortable engaging deeply in architecture reviews and technical decisions
AI-Enabled Product & Development
AI in the Product
-
Expand the use of Generative AI across patient and provider workflows
-
Scale AI-powered automation (chat/voice, document processing, operational workflows)
-
Ensure AI solutions are secure, reliable, and production-ready
AI in Engineering
-
Drive thoughtful adoption of AI-assisted development tools
-
Improve SDLC efficiency through automation and modern tooling
-
Build engineering practices that effectively leverage AI
Candidate Profile
-
15+ years of software engineering experience
-
6+ years leading large engineering organizations (50-150+ engineers)
-
Strong technical depth in cloud-native distributed systems (AWS preferred)
-
Experience deploying AI/ML or GenAI solutions in production environments
-
Track record of improving execution, quality, and engineering effectiveness
You are:
-
Technically strong and comfortable being in the weeds when needed
-
Detail-oriented and execution-focused
-
Low-ego, Calm, pragmatic, and decisive
-
Experienced leading in fast-paced, growth environments
-
Focused on raising standards without adding unnecessary bureaucracy
Additional Content
Vice President of Engineering, UX/Commercial Applications
Reports to: SVP, UX Products & Engineering
Organization Size: 100+ Engineers
Position Summary: Natera is seeking a Vice President of Engineering, UX/Commercial Applications to lead a 100+ person engineering organization responsible for our commercial software platforms. This leader will focus on strengthening execution, raising engineering standards, and advancing AI-enabled product and development capabilities.
Scope includes:
-
Patient and Provider Portals
-
EMR integrations & interoperability
-
Internal service and operational systems
-
Omni-channel communications
-
Billing and revenue platforms
-
AI-powered chat and voice automation
Key Responsibilities
Engineering Leadership & Execution
-
Lead and scale a 100+ engineer organization through Directors and Sr. Directors
-
Improve delivery predictability, engineering velocity, and production quality
-
Strengthen planning, estimation, and development processes
-
Raise the bar on accountability and ownership
-
Develop strong engineering leaders and succession depth
Technical Depth & Architectural Rigor
-
Strong background in distributed systems and cloud-native architectures (AWS preferred)
-
Experience building scalable, highly available platforms
-
Deep understanding of modern web stacks (APIs, React, TypeScript, services)
-
Experience leading platform modernization and reliability improvements
-
Comfortable engaging deeply in architecture reviews and technical decisions
AI-Enabled Product & Development
AI in the Product
-
Expand the use of Generative AI across patient and provider workflows
-
Scale AI-powered automation (chat/voice, document processing, operational workflows)
-
Ensure AI solutions are secure, reliable, and production-ready
AI in Engineering
-
Drive thoughtful adoption of AI-assisted development tools
-
Improve SDLC efficiency through automation and modern tooling
-
Build engineering practices that effectively leverage AI
Candidate Profile
-
15+ years of software engineering experience
-
6+ years leading large engineering organizations (50-150+ engineers)
-
Strong technical depth in cloud-native distributed systems (AWS preferred)
-
Experience deploying AI/ML or GenAI solutions in production environments
-
Track record of improving execution, quality, and engineering effectiveness
You are:
-
Technically strong and comfortable being in the weeds when needed
-
Detail-oriented and execution-focused
-
Low-ego, Calm, pragmatic, and decisive
-
Experienced leading in fast-paced, growth environments
-
Focused on raising standards without adding unnecessary bureaucracy